背景：该研究的目的在于评价我们采用70岁以上的老年供体行原位肝脏移植（OLT）的经验。患者和方法：在8年内我们采用70岁以上的老年供体对16例成人患者进行了原位肝脏移植。结果：供体的中位年龄为73岁（范围为70-83）。11名供者（64.7%）有过至少1次低血压期并接受血管活性药物。平均冷缺血和热缺血时间分别为7.25小时和35分钟。2名患者由于移植物失功和原发性移植物无功能而行再次移植。死亡率为47%，住院死亡率为23.5%。在平均随访34.5个月（范围为3-84个月），有其他5名患者丝袜。平均患者生存时间为17个月（范围为0-84个月）。1、3、5、7年累积生存率分别为69.7%、57.5%、46.2%以及23.3%。通过多元分析发现仅仅移植物失功是生存率的独立预测因素（P=0.042）。结论：虽然超过70岁的供者扩大了供体的范围，但是其长期生存率相比于那些年轻供者来说依然不尽理想。

BACKGROUND: The purpose of this study was to evaluate our experience with orthotopic liver transplantation (OLT) using grafts from septuagenarians. PATIENTS AND METHODS: Seventeen adult patients underwent transplantation with grafts from donors 70 years of age or older during an 8-year period. RESULTS: The median donor age was 73 years (range, 70-83). Eleven (64.7%) donors had experienced at least 1 hypotensive period and received vasoactive drugs. Median cold and warm ischemia times were 7.25 hours and 35 minutes, respectively. Two recipients underwent retransplantation because of dysfunction or primary nonfunction. Morbidity rate was 47% and hospital mortality rate was 23.5%. After a median follow-up of 34.5 months (range, 3-84 months), 5 additional patients died. Median patient survival was 17 months (range, 0-84 months). One-, 3-, 5-, and 7-year cumulative survival rates were 69.7%, 57.5%, 46.2%, and 23.3%, respectively. Only graft dysfunction (P = .042) was observed to be an independent predictor of survival upon multivariate analysis. CONCLUSIONS: Although grafts from septuagenarians allow for expansion of the donor pool, long-term recipient survival is inferior to that encountered with younger donors.